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Advanced processing of ophthalmologic videosequences of retinal images
Říha, Pavel ; Odstrčilík, Jan (referee) ; Jan, Jiří (advisor)
The diploma thesis deals with registration and analysis of images from the experimental low-cost fundus camera that reaches a low SNR (around 10 dB) and low temporal and spatial resolution. The aim of the diploma tesis is to explore the possibilities of digital processing leading to the creation of a videosequence that has real benefits for medical diagnostics. The well-known program elastix is used for registration. Preprocessing filters and interpolation are implemented in Matlab. The program provides a wide range of setting options, out of which many combinations were tested and evaluated. To assess the accuracy achieved, spatial variations in the detected motion of blood-vessels are evaluated. Best results with a precision below 0.3 px were achieved by using a band-pass filter, a~suitably sized mask, rigid registration and a metric of the mutual information. Test sequences were registered precisely enough both for visual assessment and basic computational analysis. Registered sequences and the developed application that both can be used in the further development of the experimental camera are the main contributions of the diploma thesis.
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Blood vessel segmentation and modeling in fundus images
Václavík, Jan ; Odstrčilík, Jan (referee) ; Kolář, Radim (advisor)
Studies of the vascular tree in the retina have applications not only in the medical field but also biometrics. The mathematical description of the retinal vasculature could help facilitate and improve the diagnosis of certain diseases, their automatic localization or to accelerate the identification and verification of individuals. The aim is to design and develop an algorithm that will automatically approximate major retinal vessels by parabolic, linear and kvartic functions. The main part of this thesis is therefore devoted to this issue, including vascular segmentation using Gabor filters, morphological erosion, thresholding, skeletonization and the resulting optimization of the approximation model. The quality of the produced algorithm is discussed in the summary.
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Modelling of the Visual Perception
Faruga, Michal ; Hemzal, Dušan (referee) ; Kolář, Radim (advisor)
This diploma thesis considers with human vision and human eye. It takes into account both anatomic view and physiology standpoints. There is, among others, description of optical processes occurring in the organ of the sight mentioned in the work. The human eye suffers from optical defects – aberrations – that are able to degrade the retinal image and ultimately visual performance. Substantial part of the text deals with these aberrations. There are also analysed possibilities of their elimination using an inverse aberration. Work also assumes opportunity to optical modeling to calculate distorted images from ocular aberration data. Practical part consist of software application created using Matlab environment ver. 6.5 as well as full documentation. The examples of outputs procured using this application are published. Both software application and detail documentation are included on CD.
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Advanced processing of ophthalmologic videosequences of retinal images
Říha, Pavel ; Odstrčilík, Jan (referee) ; Jan, Jiří (advisor)
The diploma thesis deals with registration and analysis of images from the experimental low-cost fundus camera that reaches a low SNR (around 10 dB) and low temporal and spatial resolution. The aim of the diploma tesis is to explore the possibilities of digital processing leading to the creation of a videosequence that has real benefits for medical diagnostics. The well-known program elastix is used for registration. Preprocessing filters and interpolation are implemented in Matlab. The program provides a wide range of setting options, out of which many combinations were tested and evaluated. To assess the accuracy achieved, spatial variations in the detected motion of blood-vessels are evaluated. Best results with a precision below 0.3 px were achieved by using a band-pass filter, a~suitably sized mask, rigid registration and a metric of the mutual information. Test sequences were registered precisely enough both for visual assessment and basic computational analysis. Registered sequences and the developed application that both can be used in the further development of the experimental camera are the main contributions of the diploma thesis.
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|
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Blood vessel segmentation and modeling in fundus images
Václavík, Jan ; Odstrčilík, Jan (referee) ; Kolář, Radim (advisor)
Studies of the vascular tree in the retina have applications not only in the medical field but also biometrics. The mathematical description of the retinal vasculature could help facilitate and improve the diagnosis of certain diseases, their automatic localization or to accelerate the identification and verification of individuals. The aim is to design and develop an algorithm that will automatically approximate major retinal vessels by parabolic, linear and kvartic functions. The main part of this thesis is therefore devoted to this issue, including vascular segmentation using Gabor filters, morphological erosion, thresholding, skeletonization and the resulting optimization of the approximation model. The quality of the produced algorithm is discussed in the summary.
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Modelling of the Visual Perception
Faruga, Michal ; Hemzal, Dušan (referee) ; Kolář, Radim (advisor)
This diploma thesis considers with human vision and human eye. It takes into account both anatomic view and physiology standpoints. There is, among others, description of optical processes occurring in the organ of the sight mentioned in the work. The human eye suffers from optical defects – aberrations – that are able to degrade the retinal image and ultimately visual performance. Substantial part of the text deals with these aberrations. There are also analysed possibilities of their elimination using an inverse aberration. Work also assumes opportunity to optical modeling to calculate distorted images from ocular aberration data. Practical part consist of software application created using Matlab environment ver. 6.5 as well as full documentation. The examples of outputs procured using this application are published. Both software application and detail documentation are included on CD.
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